Glutamate is a fast excitatory transmitter in mammalian brains. 谷氨酸是哺乳动物脑中的兴奋性递质。
Glutamate is the predominant excitatory nerve transmitter substances but a potential excitotoxin in the same time owing to causing damage even death of nerve cells when it is overdosed. 谷氨酸是视网膜内主要的兴奋性神经递质,也是一种潜在的兴奋性毒素,过量将导致神经细胞的死亡,其毒性作用呈剂量依赖性。
BACKGROUND: Glutamic acid is an excitatory transmitter in the sensory afferent fibers, and its receptors widely exist in central and peripheral nerve system, which has specific distribution in spinal dorsal neuron to mediate peripheral traumatic information transmission. 背景:谷氨酸是感觉传入纤维的兴奋性递质,其受体广泛存在于中枢和外周神经系统,在脊髓背角神经元上有特异性分布,介导外周伤害性信息的传递。
Sound stimulus and drug application both may affect not only excitatory inputs by regulating neural transmitter release but also membrane properties of a neuron by changing ion channels. 声音信号和药物施加均会影响控制神经递质释放的兴奋性输入,也会改变受离子通道影响的神经元膜特性。